Home / HEALTH / Oxford Cancer Biomarkers partners with Mira Precision Health to advance its ToxNav® test for predicting patient toxicity to 5FU/capecitabine treatment in the USA

Oxford Cancer Biomarkers partners with Mira Precision Health to advance its ToxNav® test for predicting patient toxicity to 5FU/capecitabine treatment in the USA

Oxford Cancer Biomarkers partners with Mira Precision Health to advance its ToxNav® test for predicting patient toxicity to 5FU/capecitabine treatment in the USA


In a significant advancement for cancer treatment and patient care, Oxford Cancer Biomarkers Ltd (OCB) has announced a partnership with Mira Precision Health Inc. This collaboration aims to bolster the use of OCB’s ToxNav® test in the United States, particularly focusing on predicting patient toxicity associated with commonly used cancer treatments like 5-fluorouracil (5FU) and capecitabine.

The ToxNav® test represents a breakthrough in precision oncology, targeting the critical need to identify patients who are at high risk of severe side effects from these drugs. The potential for extreme toxicity from 5FU and capecitabine can lead to serious health complications or even death. Given the widespread use of these drugs in cancer treatment, the implications of the ToxNav® test could be profound, enhancing patient safety, improving treatment outcomes, and ultimately saving lives.

Headquartered in Mason, Ohio, Mira Precision Health is dedicated to enriching precision medicine through innovative solutions tailored for healthcare providers. With its expertise in clinical workflows and diagnostic solutions, the partnership with OCB marks a pivotal moment in advancing ToxNav® across the United States. The goal is not only to establish a significant market presence but also to refine clinical decision-making processes, thereby improving overall cancer care.

Dr. David Kerr, the founder and director of OCB, expressed his enthusiasm for this collaboration, stating that the ToxNav® test has already proven its efficacy in identifying patients vulnerable to extreme toxicity. He emphasized OCB’s excitement about partnering with an organization that shares complementary knowledge to expand the clinical utility of the ToxNav® test. OCB’s vision aligns with a growing movement toward personalized cancer care, where treatment plans are tailored to individual patient needs based on their genetic makeup and potential responses to therapies.

Mira Precision Health’s founder and CEO, Dr. Sandra Gunselman, echoed these sentiments. She expressed her commitment to delivering innovative diagnostic solutions that will enhance patient care and streamline clinical practices. By bringing together expertise from both organizations, this partnership aims to significantly impact patient outcomes across the U.S. healthcare system.

Furthermore, the recent updates to the National Comprehensive Cancer Network (NCCN) guidelines reinforce the need for comprehensive screening before administering fluoropyrimidine-based treatments. These guidelines now recommend thorough testing for DPD (dihydropyrimidine dehydrogenase) deficiency, a genetic condition that can complicate treatment with drugs like 5FU and capecitabine, thereby adding urgency to the implementation of ToxNav® in clinical settings.

Shaun Peterson, Vice President of Sales and Marketing at Mira Precision Health, remarked on the timely relevance of the ToxNav® test amidst updates in NCCN guidelines. He pointed out that the ToxNav® test is backed by numerous peer-reviewed studies and holds CE-IVD certification in the UK, affirming its reliability and efficacy. The test not only aims to enhance patient outcomes but also has the potential to reduce healthcare costs through more targeted, effective treatment strategies.

This partnership is further vitalized by community support, such as from Karen Merritt, co-founder of Advocates for Universal DPD/DPYD Testing, who highlighted the importance of preventing avoidable toxicity through better screening methods. Her endorsement signifies a growing recognition of the need for standardized protocols in treating patients with cancer drugs.

The City of Mason has also shown enthusiasm for its collaboration with Mira Precision Health. Michele Blair, the Director of Economic Development, emphasized the city’s commitment to fostering science partnerships that can lead to rapid commercialization of health technologies. The success of the ToxNav® test is expected to contribute positively to local and national health outcomes.

Overall, the partnership between Oxford Cancer Biomarkers and Mira Precision Health represents a significant step toward achieving safer cancer treatment protocols. The ToxNav® test can pave the way for more informed, personalized treatment options for cancer patients while simultaneously addressing concerns regarding treatment side effects. As they continue to collaborate, this initiative may set new standards in oncology, transforming patient care and broadening access to advanced predictive diagnostics.

The implications for this collaboration extend beyond traditional academic settings. By integrating cutting-edge research with clinical practice, OCB and Mira Precision Health are positioning themselves at the forefront of precision medicine. This could potentially serve as a model for future partnerships in the healthcare industry, where innovation and collaboration drive improvements in patient outcomes.

As healthcare providers and patients look toward an era of increasingly personalized cancer treatment, the ToxNav® test stands to enhance decision-making capabilities in clinical environments significantly. Oxford Cancer Biomarkers and Mira Precision Health’s commitment to innovation and collaboration could ultimately redefine how cancer therapies are approached, potentially transforming the treatment landscape for patients across the United States.

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