As the 2025 NFL season approaches, excitement is building among fans and sports bettors alike. Opening week promises thrilling matchups, including the Cowboys facing off against the Eagles, and the Ravens squaring off with the Bills under the lights. Below, we delve into notable player and team prop bets, focusing on popular sportsbooks like FanDuel, to help you get started with your Week 1 betting strategy.
Key Matchups and Prop Bets
Cowboys @ Eagles
This matchup is set to be one of the highlights of the opening week.
- Jalen Hurts & Saquon Barkley to combine for 3+ rushing TDs: +430
- Saquon Barkley anytime touchdown: -165
- Dak Prescott 250+ passing yards: +110
- CeeDee Lamb anytime touchdown: +160
Insights:
Barkley had an impressive 13 rushing touchdowns last season, with two coming in Week 1. Hurts topped all quarterbacks with 14 rushing touchdowns last year, showcasing both players’ ability to find the end zone on the ground. Prescott’s relationship with Lamb has shown potential, with Dak passing 250 yards in three of his last eight games.
Chiefs @ Chargers
Another game attracting attention is between the Kansas City Chiefs and the Los Angeles Chargers.
- Patrick Mahomes & Justin Herbert to combine for 6+ passing & rushing TDs: +700
- Patrick Mahomes O246.5 passing yards: -114
- Travis Kelce anytime TD scorer: +150
Insights:
Despite Mahomes experiencing a drop in touchdowns last season, he still surpassed 246 passing yards in nine games. Herbert also had standout performances, including multiple touchdowns in key games. With talks of Kelce’s engagement to Taylor Swift, many fans wonder if this could be the final chapter of the Chiefs’ current dynasty.
Steelers @ Jets
When the Steelers clash with the Jets, player props can be intriguing.
- Justin Fields anytime TD scorer: +240
- Aaron Rodgers 2+ passing TDs: +130
- Aaron Rodgers 200+ passing yards: -152
Insights:
Fields had a total of 10 touchdowns last season and showed his dual-threat capability. Rodgers consistently threw for over 200 yards and two or more touchdowns in numerous games last season, indicating that both quarterbacks could shine in this matchup.
Giants @ Commanders
This NFC East rivalry will add to the Week 1 excitement.
- Terry McLaurin anytime TD scorer: +105
- Jayden Daniels 225+ passing yards: -130
- Russell Wilson 225+ passing yards: +102
Insights:
McLaurin, having recently signed a contract extension, is poised to make an impact in this game. Daniels has shown promise in his last few outings, while Wilson continues to aim for consistent performances as he adjusts to his new team.
49ers @ Seahawks
The clash of these two rivals promises to be intense.
- Christian McCaffrey to score 2+ TDs: +350
- Brock Purdy 2+ passing TDs: -132
- Sam Darnold 275+ passing yards: +182
Insights:
McCaffrey is a proven scorer, having multiple multi-TD games under his belt. Purdy’s consistency and Darnold’s solid season last year make them attractive options for player props.
Lions @ Packers
As the season kicks off, expect fireworks.
- Jordan Love 3+ passing TDs: +370
- Jared Goff 300+ passing yards: +350
Insights:
With Love stepping into a pivotal role and Goff having numerous high-yardage games, this game could produce exciting scoring opportunities.
Ravens @ Bills
This anticipated showdown features some of the league’s most dynamic quarterbacks.
- Josh Allen & Lamar Jackson to combine for 3+ rushing TDs: +1000
- Josh Allen 275+ passing yards: +220
- Lamar Jackson 275+ passing yards: +225
Insights:
Both quarterbacks had stellar seasons, and betting on their rushing capabilities alongside passing yards presents considerable value.
Vikings @ Bears
As we wrap up Week 1, keep an eye on rookie sensations.
- Caleb Williams 2+ passing TDs: +114
- J.J. McCarthy 250+ passing yards: +182
Insights:
Both rookies are stepping into significant roles early in their careers, making this matchup particularly interesting for prop bets.
Prop Bet Trends
Most Passing Yards in Week 1:
- Joe Burrow: +600
- Baker Mayfield: +950
- Patrick Mahomes: +1100
This list shows quarterbacks who consistently deliver high-performing games. Burrow, in particular, had an impressive last season and could carry that into the beginning of this season.
Team with the Highest Total Points in Week 1:
- Eagles: +900
- Bills: +900
Betting markets expect high-scoring games from these teams, who have shown explosive offensive capabilities in recent seasons.
Team with the Lowest Total Points in Week 1:
- Titans: +700
- Jets: +700
These teams have shown inconsistency, which opens up opportunities to bet on lower scoring outcomes.
Conclusion
Week 1 of the 2025 NFL season is shaping up to be electrifying, with numerous player and team prop bets available. As the games approach, bettors should stay updated on player performances, injury reports, and team dynamics. There’s a balance between making informed decisions and enjoying the excitement that comes with the opening week of football. Whether you’re a seasoned bettor or enjoying the games casually, this is just the start of what promises to be an exhilarating season. Happy betting!
